JAEA's action on medical RI production using research reactor

Arai, Masaji; Maeda, Shigetaka

Rinsho Hoshasen, 68(10), p.963 - 970, 2023/10

Ac-225 is attracting attention as an alpha-emitting medical radioisotope. Since its demand is expected to increase, domestic production of Ac-225 is required from the viewpoint of Japan's medical research and economic security. To establish the technical bases for the Ac-225 production, JAEA has evaluated the radioactivity that can be produced in the experimental fast reactor Joyo and designed the concept that upgrades the existing facilities for transporting the irradiated target from Joyo to a neighboring PIE facility rapidly. Efficient Actinium-225 Separation from Ra-226 irradiated in a fast reactor was studied. This study has revealed that Joyo can sufficiently produce Ac-225 as a raw material for pharmaceuticals.